![]() The most feasible explanation for the antimicrobial action of alcohol is denaturation of proteins. Their cidal activity drops sharply when diluted below 50% concentration, and the optimum bactericidal concentration is 60%–90% solutions in water (volume/volume) 483, 484. These alcohols are rapidly bactericidal rather than bacteriostatic against vegetative forms of bacteria they also are tuberculocidal, fungicidal, and virucidal but do not destroy bacterial spores. ![]() FDA has not cleared any liquid chemical sterilant or high-level disinfectant with alcohol as the main active ingredient. ![]() ![]() In the healthcare setting, “alcohol” refers to two water-soluble chemical compounds-ethyl alcohol and isopropyl alcohol-that have generally underrated germicidal characteristics 482. ![]()
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